艾美捷科技代理Ligatrap品牌全系列产品

LigaTrap Technologies是一家位于北卡罗来纳州的创新型生物技术公司，提供独特的专利技术组合，专注于蛋白质纯化领域。LigaTrap精于抗体与病毒纯化，服务于抗体药物、病毒疫苗及基因治疗产业。

▍LigaTrap公司产品

● LigaGuard：最新推出的亲和吸附剂，是由多模态配体构成的专利复合体系，可在流穿模式（连续流）下选择性捕获宿主细胞蛋白（HCPs）与DNA。

● AAVidity™：一种新型亲和层析填料，用于血清型普适性纯化 源自 HEK293 和 Sf9 细胞裂解液 的 腺相关病毒（AAV）。

● IgM Resin：专为纯化 IgM 抗体设计的亲和树脂，具有高纯度、高结合能力、温和的洗脱条件（pH 约 4.0），并可重复使用多达 100 次。

● Base Resin：专为从多克隆与单克隆来源中纯化高质量抗体而设计，该树脂推荐用于纯化：多种物种的 IgG（包括人、小鼠、兔等）；人源 IgA；鸡源 IgY。

● LigaTrap Buffers：包含Regeneration Buffer，Neutralization Buffer，Elution Buffer，Regeneration Buffer，Equilibration/Wash Buffer 2.0等。

▍LigaGuard

LigaGuard™树脂适用于两类核心产品的纯化：蛋白制品：单克隆抗体、生长因子；病毒制品：慢病毒、腺相关病毒（AAV）、病毒疫苗。该树脂的设计使目标生物产物无结合通过，实现高纯度与高回收率。其能清除传统纯化工艺难以去除的高残留性HCPs（HR-HCPs），显著提升终产物的纯度、稳定性、疗效与安全性。

▍AAVidity

AAVidity填料通过合成亲和配体功能化修饰，可捕获所有血清型的 AAV，提供卓越的结合载量与污染物（宿主细胞蛋白 HCPs 及宿主细胞DNA hcDNA清除能力。其温和洗脱条件在保障 AAV 转导活性的同时，实现高产物回收率。

▍IgM Resin

 IgM纯化树脂的核心优势包括：

● 全面捕获：同时结合IgM的重链与轻链亚型；

● 零风险：无免疫原性及配体脱落；

● 活性保全：温和洗脱条件保障抗体完整性；

● 经济耐用：消毒再生后可重复使用 ≥100 次；

● 该树脂能高效处理并纯化来自以下样本的单克隆 IgM：细胞培养上清，腹水，杂交瘤，其他重组 IgM 来源。

▍Base Resin

LigaTrap基础纯化树脂可实现高回收率与>95%的纯度，而传统Protein A和Protein G填料的回收率甚至低于检测限。通过优化工艺，该树脂的纯度可进一步提升至99%。

▍Buffers

Taking advantage of technologies and expertise long cultivated by the Nittobo Group, the Environment & Health Division operates a comprehensive range of business operations. In the medical field, we develop reagent for in vitro diagnostics in three fields: biochemistry, hematology, and immunology. The specialty chemicals business focuses on the development of polymer and a comprehensive range of applications. The beverage business is based on private brands and is engaged in the complete process from molding of PET bottles to manufacturing and bottling of beverages. For the green business, we sell rock wool substrate for agriculture and horticulture (made by Rockwool B.V.).

Nittobo的主要产品包括：

Textiles

Glass Fiber

Environment & Health

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美国Plant Cell Technology公司为商业及研究用植物组织培养实验室和植物种植者开发、生产了旗舰产品PPM™ (Plant Preservative Mixture)，它是一种广谱抗微生物剂，可以杀死细菌和真菌细胞，防止真菌孢子的萌发，并在较高浓度下能消除内源性污染的外植体。研究表明PPM™活性成分可以渗透过真菌或细菌细胞壁，抑制柠檬酸循环和电子传递链等中心代谢循环中的关键酶的活性，并且可以抑制培养基中的单糖和氨基酸向真菌和细菌细胞的运输。PPM™能有效地抑制植物细胞和植物组织培养中的通过空气、水、人传播的微生物污染及内源性污染，而不会影响体外种子发芽、愈伤组织增殖和愈伤组织的再生。并且，PPM™具有热稳定性，可以和培养基一起灭菌，同时比常用抗生素价更低廉，可以作为植物组织培养基的标准成分。

The principal PCT scientist involved in the development of the PPM™ application is Dr. Assaf Guri. Dr. Assaf Guri holds degrees in genetics, applied genetics and plant breeding from the Hebrew University in Jerusalem and Michigan State University in the US. Before joining Plant Cell Technology, Inc., Dr. Guri worked with the Volcani Agricultural Research Center in Israel, Michigan State University in East Lansing, Michigan and DNAP in New Jersey.

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Laysanbio专业提供聚乙二醇类产品，包括多臂聚乙二醇，亲核聚乙二醇，羧基聚乙二醇，亲电型聚乙二醇类，亲电型琥珀酰亚胺基聚乙二醇类，巯基聚乙二醇类。

Laysan Bio, Inc. (Laysan) is a Biotechnology company that offers novel polymers to customers for development of a wide variety of platforms. The management team and key employees have been involved with the development and supply of PEG reagents for seven FDA or EU approved drug products or medical devices including Neulasta®, Somavert®, PEGASYS®, PEG-INTRON®, Definity®, Macugen® and DuraSeal™.

主要产品包括：

Acrylates (ACRL)

Aldehydes (bALD, pALD)

Amines (NH2)

Biotins (BIO)

Carboxylic Acids (COOH, ASA)

Epoxides (EPOX)

Esters (NHS, SAS, SC, SCM, SG, SS, SVA)

Hydrazides (HZ)

Hydroxyls (OH)

Kits of PEG reagents

Maleimides (MAL)

Multi-Arms (4 arm)

Nitrophenyl Carbonates (NPC)

Orthopyridyl Disulfide (OPSS)

Phospholipids (DSPE)

Protected Amines (FMOC, tBOC)

Silane (SIL)

Thiols (SH)

Valeric Acids (VA)

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Celprogen是一家生物技术公司，为心脏病学、肿瘤学、糖尿病和神经病学的再生医学研发干细胞研究和治疗产品。Celprogen的所有生物产品，包括干细胞、癌症干细胞、IPC和包括ECM在内的培养基，均在美国制造和生产。

CELPROGEN is a biotechnology company developing stem cell research and therapeutics products for regenerative medicine in cardiology, oncology, diabetes & neurology. All of Celprogen’s biological products, including stem cells, cancer stem cells, iPC’s & media including ECM’s, are manufactured and produced in the United States of America. CELPROGEN provides novel molecular diagnostics and therapeutic product development solutions for Biotechnology, Pharmaceutical, Invitro diagnostics and academic partnership for drug discovery.

Celprogen公司的主要产品：

3D Culture Systems

Biological Reagents

Cell-Based Assay Kits

Cosmetic

Devices

ExtracellularMatrix

Human Serum Albumin (HSA)

Life Science

Normal Cells

Organ Cultures

Patient-Derived Xenografts [PDX]

Therapeutics

Tumorgenicity

Vaccine Development

Xeno-Free Media

在诊断领域，Generon拥有数百个产品，主要包括抗体、组织染色切片、FISH、CISH探针、qPCR&NGS试剂盒等，针对分子生物学、二代测序、组织学、原位杂交、流式细胞学等应用，所有这些诊断产品均拥有CE/IVD认证，可以确保临床应用中的准确性。在研究领域，Generon拥有上百万个产品，主要是针对分子生物学、NGS、2D、3D细胞培养、免疫检测、色谱、电泳等实验的抗体、ELISA试剂盒等。

Generon’s catalog includes several hundred products for diagnosis and medical biology. Our products cover a wide range of applications and field of medical diagnostics. We want to offer you all the products you need to move your projects forward. Applications: molecular biology, NGS, histology, in situ hybridization, flow cytometry ... Types of products: Antibodies, tissue stains, probes for FISH and CISH, qPCR and NGS kits, culture media.... All our medical diagnostic products are CE / IVD-certified (In Vitro Diagnostic) to ensure quality and follow-up for reliable results in diagnosis and choosing the right treatment.

Generon’s catalog includes millions of products for research in the life sciences. Our products cover a wide range of applications and research areas. We want to offer you all the products you need to move your projects forward. Applications: Molecular biology, NGS, 2D and 3D cell culture, immunoassays, chromatography, electrophoresis ... Types of products: Antibodies, ELISA kits, PCR Enzymes, particles, tetramers, disinfectants ...

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Vally Biomedical自1986年建立之初，就开始为客户提供高质量的生物、诊断试剂，并进行合作生产。1995年，Valley Biomedical利用自身的技术经验，为研发客户提供一些列人和动物源的血液制品和细胞培养血清等产品。

Valley Biomedical was established in 1986 to service the Clinical Diagnostics Industry with high quality biologicals, diagnostic reagent products and contract manufacturing services. Around 1995 we began to utilize our depth of experience and concentrate on providing a line of Human and Animal source blood products and cell culture sera to the R&D market.

Valley Biomedical的主要产品包括：

（1）CELL CULTURE

Human Serum

Fetal Bovine Serum

Other Animal Sera

Albumin

Liquid Media Products

（2）Human Products

Human Blood

Human Plasma

Human Serum

Other Human Prod.

（3）Animal Products

Dog

Rat

Mouse

Rabbit

Monkey

Guinea Pig

Equine

Sheep

Minipig

Porcine

Other

（4）REAGENTS

Aqueous Solutions

Media

Clinical Lab Products

Contract Manufacturer

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艾美捷科技特约代理Epigentek公司产品。

Epigentek公司是全球领先的表观遗传学相关研究的技术创新者和产品开发供应商。公司开发了700多个专利产品，为表观遗传学方面的研究和新药研发提供全面系统的解决方案。相比普通方法的产品而言，这些独特的产品在科研分析过程中更简单、更快捷、更方便、更有效。全世界的备受推崇的学者、领先的制药企业以及先进的生物技术公司都在使用Epigentek产品。让客户满意和帮助客户在试验中取得最大成功是我们进行技术创新的首要任务。

As an epigenetics company, Epigentek Group Inc. is the leading developer and provider of innovative technologies and products for epigenetic-related research. Founded in 2005, the company has since developed a comprehensive portfolio of proprietary products to provide complete and systematic solutions for epigenetics-related research and drug discovery.

Epigentek products are used all around the world by esteemed academia, leading pharmaceuticals, and cutting-edge biotechnology companies. These unique products are specifically designed to make assays much simpler, faster, more convenient, and highly more efficient than currently used methods.

产品主要有：

（1）Antibodies

DNA Methylation

Histone Modification

RNA Processing & Modification

Chromatin & Transcription

Cellular Structure & Function

Signal Transduction

Metabolism

Immunology & Inflammation

Other Primary Antibodies

Secondary AntibodiesTag Antibodies

Antibody Panel Packs

（2）Research Kits

Sample Preparation

Next Generation Sequencing

DNA Methylation

RNA Methylation

Chromatin & Transcription

Histone Methylation

Histone Acetylation

DNA Damage & Repair

Gene Editing & Silencing

（3）Proteins & Enzymes

DNA Methylation

Modified Histones

Unmodified Histones

Methylated DNA Binding

ADP Ribose

Chromatin Binding/Transcription

DNA Damage & Repair

（4）Peptides

Histone Methylation

Histone Acetylation/Deacetylation

Histone Phosphorylation

（5）Modulators & Inhibitors

DNA Methylation

Histone Acetylation

Histone Deacetylation

Histone Demethylation

Histone Phosphorylation

（7）Reagents

（8）Instruments

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艾美捷科技代理NanoLight Technology品牌。

NanoLight Technology公司致力于开发天然发光海洋蛋白（海洋生物发光）的应用。NanoLight® 技术的生命科学应用包括：高通量药物发现、功能基因组学、肿瘤成像、放射性同位素替代、光遗传学、分子诊断等。自2012年以来，NanoLight Technology公司主要提供无毒、水溶性的生物发光底物，用于体内成像领域，以监测小鼠模型中的肿瘤生长。另一个非常新的应用是光遗传学领域，它为神经科学家提供了使用生物发光控制神经元的惊人能力。NanoLight Technology公司研究团队不断扩大产品组合。Prolume Purple（美国专利 9,624,425），是一种新型底物，其性能优于广泛用于研究蛋白质-蛋白质相互作用的 DeepBlueC™。除了基本的生物发光化合物外，NanoLight 还将这些底物整合到复杂的缓冲系统中，适用于具有不同动力学特性的各种荧光素酶，为研究人员提供便利，并为制药公司的自动化高通量筛选提供可靠的批次控制试剂。NanoLight 也是开发分子靶标传感工具的领导者。NanoLight 提供迄今为止已知的两种最亮荧光素酶——高斯荧光素酶（GLuc-SA）和 Oplophorous 荧光素酶（NLuc-SA）的链霉亲和素偶联物，便于检测生物素化分子（如 DNA、RNA、肽、蛋白质）。

TiterMax®佐剂被用于增强免疫反应。TiterMax®佐剂有着跟弗氏佐剂相同的功效，但具有更安全、更易用的特点，是弗氏佐剂的理想代替产品。

TiterMax® adjuvants are used to produce cell mediated and humoral responses in research animals. TiterMax® adjuvants were developed to meet the specific needs of investigators for immunoadjuvants that are at least as effective as Freund's Complete Adjuvant, safer and easier to use. They are an attractive alternative to Freund's Complete Adjuvant for use by researchers in inducing antibody to diverse antigens. The key to the potency of TiterMax® adjuvants lies both in the immunostimulatory activity of their components and in the fact that they form a stable water-in-oil emulsion. TiterMax® adjuvants contain three essential ingredients: Proprietary block copolymers, squalene, a metabolizable oil, and a unique microparticulate stabilizer. Like Freund's Complete Adjuvant, TiterMax® adjuvants can be used with a wide variety of antigens because they can entrap any antigen in a water-in-oil emulsion. TiterMax® adjuvants aid in the antigens effective presentation to the immune system without the toxic effects of Freund's Complete Adjuvant.

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