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Nanoprobes.jpg

Nanoprobes公司专业生产免疫金标记和免疫测定试验产品。其独特的金标技术使用化学交联的金属和纳米颗粒团簇作为标记。与胶体金颗粒静电吸附在抗体和蛋白质上的传统免疫金探针不同,本公司的金标是与生物分子在特定位点交联的不带电荷的分子。这使我们的探针具有胶体金不具备的范围和灵活性。我们的标记可以附着在任何带有反应基的分子上– 蛋白质、多肽、寡核苷酸、小分子和脂类 - 以检测和定位这些分子。其他标记可以与我们的金标共同使用,我们独特的荧光纳米金探针在一个探针中结合了纳米金(nanogold®)和荧光素,用于荧光和电镜两种技术共同进行样品成像。

 

Nanoprobes was founded in 1990 by Dr. James F. Hainfeld, along with a group of scientists who were also alumni of Brookhaven National Laboratory. The independent research facility they formed has allowed Dr. Hainfeld and his colleagues the freedom to pursue some of the greatest challenges in research: seeking cures for cancer and other diseases.

 

While part of the funding for these endeavors has come from research grants, another source had to be found, as the scientific community faces ever-increasing government cutbacks. To this end, Nanoprobes began to offer many of the nanoparticle technologies developed by its members for use in other scientists' research.

 

Nanoprobes公司主要产品:

AuroVist™ 15 nm & 1.9 nm X-ray Contrast Agent

Conjugates

Enhancement / Developers

EnzMet™ ultra-sensitive

Gold Nanomaterials: Functionalized Nanoparticles

Gold Nanoparticle Reagents

Histadine (His) Tag Labeling

Recombinant Protein Detection

FerroMag™ Magnetic nanoparticles

Negative Stains for EM

Xray Contrast Agents

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全国服务热线:400-6800-868

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艾美捷科技代理Clearsynth品牌全系列产品


Clearsynth研发中心位于海得拉巴,以“创新与精准之心”为核心理念,打造了一个精心设计的空间,旨在激发突破性的发现并提升可能性的界限。专注于创新有机化学和独特复杂分子的合成,涵盖稳定同位素标记化合物、代谢物、杂质、葡萄糖醛酸、手性化合物、共轭物杂质和放射性标记化合物等。承接复杂分子或“难以合成”的合成化合物/中间体的定制合成服务。提供超过3,59,000个高纯度参考标准品,Clearsynth公司的产品线包括稳定同位素、原料药、杂质、亚硝胺、二级标准、散装化合物等。


Clearsynth页面.png


Clearsynth服务领域

● 小分子:合成各种精细化学品和化合物,用于从毫克到数公斤规模的小分子药物发现。

● 工艺开发:开发新的合成路线,也可以修改和优化客户提供的工艺。

● 合同研发综合:专注于从临床前阶段到III期以及成功的技术转让。

● 生物核磁共振服务:位于海得拉巴的符合GLP标准的高场生物核磁共振/600MHz和300MHz设施,由敬业且经验丰富的核磁共振操作员提供支持。

● CDMO服务:致力于复杂、危险和可持续的产品和工艺。

● 分析服务:符合FDA、BIS、卫生部和其他标准机构制定的所有监管规范。


Clearsynth部分产品列表


品名货号CAS号
α-Keto Isovaleric Acid Sodium Salt 13C D6CS-R-005623715-29-5 (Unlabeled)
α-Keto Isovaleric Acid Sodium Salt 13C5CS-R-004821173018-24-0
α-Keto Isovaleric Acid Sodium Salt D6CS-R-004853715-29-5(Unlabeled)
α-Keto Isovaleric Acid Sodium Salt Dimethyl-13C2CS-R-00488634908-42-2
α-KETOBUTYRIC ACID, SODIUM 13C, D4CS-R-004752013-26-5 (Unlabeled)
α-KETOBUTYRIC ACID, SODIUM SALT 13C4, D2CS-R-00477360769-17-1
α-KETOBUTYRIC ACID, SODIUM SALT METHYL-13CCS-R-00478634908-43-3
α-KETOBUTYRIC ACID, SODIUM SALT METHYL-13C, D2CS-R-004791007476-77-8
α-Ketobutyric Acid-d2 Sodium SaltCS-T-302941007476-82-5
α-Ketoglutaric acid 13C2, D2CS-CX-00331123953-28-6
α-KETOGLUTARIC ACID 13C5CS-R-00549161096-83-9
α-KETOGLUTARIC ACID, DISODIUM SALT 13C4CS-R-004801429051-79-5
α-KETOISOCAPROIC ACID 13CCS-R-0055192751-19-4
α-KETOISOCAPROIC ACID, SODIUM SALT 13C2CS-R-005524502-00-5(Unlabeled)
α-KETOISOCAPROIC ACID, SODIUM SALT ISOPROPYL-D7CS-R-005551795020-84-6
α-Tocopherol-[13C3]CS-I-0034059-02-9 (Unlabeled)
β-ALANINE 13CCS-R-0004265138-34-3
β-ALANINE 13C, 15NCS-R-004491822942-84-6
β-ALANINE 13C3CS-R-00040107-95-9 (Unlabeled)
β-ALANINE 15NCS-R-00041204451-53-6
β-CAROTENE 13C4CS-R-005677235-40-7(Unlabeled)
-β-Cyclocitral-d5CS-T-5141078995-98-9
β-Endosulfan D4CS-O-15034203716-99-8
β-Ionone-[13C3]CS-I-0036814901-07-6 (Unlabeled)
βmethasone 17-propionate-d3CS-O-104265534-13-4 (Unlabeled)
β-Tocopherol-[13C9]CS-I-0034159-02-9 (Unlabeled)
γ-HCH D6CS-EJ-000960556-82-3
(-)-(2S,3S)-Viridifloric Acid Acetonide-d7CS-T-10281695462-09-2(Unlabelled)
(-)-(2S,3S)-Viridifloric Acid Ethyl Ester-d7CS-T-102815176712-53-1(Unlabelled)
(-)-(3S)-3-Hydroxy Quinine-vinyl-d3CS-T-1012622734920-65-9
(-)-(S)-Cibenzoline-D4CS-O-33254103419-18-7 (Unlabeled)
(-)-2-Amino-6-propionamido-d3-tetrahydrobenzothiazoleCS-T-978051217644-20-6
(-)-2-Methyl Isoborneol-d3CS-T-58298135441-89-3
(-)-alfa-Benidipine-d5 HydrochlorideCS-P-07295129262-07-3 (Unlabeled)
(-)-Cannabidiol-d9CS-TA-863221246819-21-5
(-)-Citrinin-13C,d2CS-T-728771329611-85-9


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艾美捷科技代理Accuplexdiagnostics品牌全系列产品


Accuplex Diagnostics成立于2011年,是一家专注于开发新型诊断测试的企业,其目标市场涵盖兽医、人类和研究应用领域。在产品开发和国际营销积累了超过50年的丰富经验,致力于开发新的诊断测试,旨在简化已确定需求领域的生物标志物检测。Accuplex Diagnostics在爱尔兰梅努斯大学设有校内基地,为马匹和一般兽医实践提供测试套件,体现了其产学研结合的发展模式。

Accuplex Diagnostics的产品——OmniChek-SAA™通过检测血清淀粉样蛋白A(SAA)这一炎症生物标志物能快速检测多物种炎症情况,并具有以下特征:

● 广泛适用性:可检测多种物种的炎症情况,包括狗、兔子、猫、海豹、狒狒、猴子以及生产动物等。在兽医临床、动物研究以及生产动物健康管理等多个领域有重要的应用价值。

● 快速简便:运行快速且操作简单,只需使用一滴全血即可方便地使用,大大节省了检测时间和操作成本。

● 多场景应用:除了动物检测外,还可应用于其他重要领域,为兽医、动物主人和其他相关利益者提供了一个有用的新工具,有助于及时发现和处理动物的健康问题。


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▍Accuplexdiagnostics产品列表


品名产品描述
EquiChek™-SAAEquiChek™-SAA is a simple stall-side test that provides veterinarians, trainers or breeders with the opportunity to test for any inflammatory condition, including infections, where it matters, beside the horse. Blood can be analyzed without the need to send samples to a lab. In just two simple steps, you can tell if the horse has an active inflammatory condition.
OmniChek™-SAAOmniChek™-SAA is a simple animal-side test that provides veterinarians or animal carers and owners with the opportunity to test for inflammatory conditions, including infections, where and when it matters, beside the animal in the surgery, field, or home. All that is needed is a tiny drop of blood and analysis is performed without the need of a laboratory. In just two simple steps, you can tell if the animal has an active inflammatory condition such as acute infection.
SideroTec™-Total Assay KitThe SideroTec-Total kits contains all the reagents required for Siderophore detection with sufficient materials to run up to 110 tests. It can be used for both qualitative as well as quantitative assay and can be used either manually or automated for high throughput screening. With minimal set up and rapid assay time, the SideroTec-Total assay kit is a convenient and cost-effective method for siderophore detection.
SideroTec-HiSens™ AssayThe SideroTec-HiSens™ assay uses a single addition ready-to-use fluorescent label for detection of siderophores and other iron chelation molecules in aqueous, organic, or biological  samples.
SideroTec-AsP™The SideroTec-AsP™ is an ELISA* that enables detection of the fungus Aspergillus fumigatus responsible for Invasive Aspergillosis (IA), an infection which can prove fatal to patients with other underlying conditions including those with cancer, organ transplant patients or anyone who may be immunocompromised. It is now recognised that many patients with COPD also have invasive pulmonary aspergillosis but remain undetected.During the Covid pandemic, IA caused up to 30% of all deaths in ICU.


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艾美捷科技代理VisualProtein品牌。

VisualProtein成立于2005年,致力于通过提供创新的科研产品与服务推动生物领域发展。凭借在蛋白质组学、免疫学及细胞学领域的专业深耕,不断拓宽科学研究的可能性边界。


Visual Protein的产品包括:

分类品名货号
ProteomicsWestern Blot Tool BoxBOX12
ProteomicsWestern Blot Tool Box with LuminolPen(LH03-10)BOX12-03
ProteomicsBlockPRO™ Blocking BufferBP01-1L
ProteomicsBlockPRO™ Protein-Free Blocking BufferBF01
ProteomicsBlockPRO™ 1 Min Protein-Free Blocking BufferBM01
ProteomicsLuminolPen™, HRP systemLH03
ProteomicsLumiFlash™ Prime Chemiluminescent Substrate, HRP SystemLF01-500
ProteomicsLumiFlash™ Ultima Chemiluminescent Substrate, HRP SystemLF08-500
ProteomicsLumiFlash™ Infinity Chemiluminescent Substrate, HRP SystemLF16-500
ProteomicsLumiFlash™ Femto Chemiluminescent substrate, HRP SystemLF24-100
ProteomicsExtractPRO™ Protein Extraction ReagentEP05-30
ProteomicsRIPA Cell Lysis BufferRP05
ProteomicsDual-Range™ BCA Protein Assay KitBC03-500
ProteomicsDual-Range™ Bradford Reagent (1X)BR01-500
ProteomicsDual-Range™ Bradford Reagent (5X)BR05-500
ProteomicsDual-Range™ Bradford Protein Assay Kit (5X)BR05-500-K
ProteomicsVisPRO™ Blue-One Protein StainVB01-500
ProteomicsVisPRO™ 5 Minute Protein Stain KitVP01
Proteomics6X Laemmli SDS Sample Buffer, non-reducing(without beta-mercaptoethanol)SBN06-15
Proteomics6X Laemmli SDS Sample Buffer, reducing(with beta-mercaptoethanol)SBR06-15
Immunoassay bufferImmunoEX immunoassayDevelopment Kit(TBST)IEX001
Immunoassay bufferImmunoEX ImmunoassayDevelopment Kit (TBS)IEX002
Immunoassay bufferImmunoEX TBST BufferIE01-500
Immunoassay bufferImmunoEX TBS BufferIE02-500
Immunoassay buffermmunoEX Protein-BasedImmunoassay Buffer(TBSTIE03-500
Immunoassay bufferImmunoEX Protein-Based lmmunoassay Buffer (TBS)IE04-500
Immunoassay bufferImmunoEX Protein-Free Immunoassay Buffer(TBSTIE05-500
Immunoassay bufferImmunoEX Protein-Free Immunoassay Buffer (TBS)IE06-500
SupplementCytoMore Cell RescueSupplementCTO1-1BT
SupplementHybriMore™ Hybridoma Culture Supplement*HB01-1L
BufferPBS Buffer, 10XPBS10-1L
BufferPBS Tween-20 Buffer, 10XPBST10-1L
BufferTBS Buffer, 10XTBS10-1L
BufferTBS Tween-20 Buffer, 10XTBST10-1L
BufferTBS Tween-20 Buffer, 25XTBST200P
BufferSDS-PAGE Running Buffer, 10XRB10-1L
BufferSDS-PAGE Running Buffer, powder packRB500P
BufferWestern Blot Transfer Buffer, 10XWTB10-1L
BufferWestern Blot Transfer Buffer, powder packWTB500P



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艾美捷科技代理Synthelis Biotech品牌全系列产品


Synthelis Biotech是一家法国公司,专注于蛋白质的生产、纯化与表征,公司致力于助力疫苗、生物制剂、酶、工程蛋白、诊断工具以及高通量分子或配体筛选技术的开发。Synthelis Biotech提供经过验证的蛋白质,其活性和纯度均根据特定应用(候选药物筛选、抗体与疫苗开发、结构生物学、体外诊断、蛋白质载体化)量身定制。Synthelis Biotech专利的无细胞技术使客户能够从不同蛋白家族(GPCRs、离子通道、转运蛋白等)和不同形式(蛋白脂质体、纳米盘、去垢剂溶解形式或可溶形式)中选择合适的蛋白质。凭借其专利技术,Synthelis 能够在数小时内合成各类蛋白质:包括膜蛋白、毒性蛋白、修饰蛋白等,应用于药物筛选、疫苗与抗体开发、结构生物学以及体外诊断等领域。同时可按需进行修饰(荧光或同位素标记、非天然氨基酸掺入、截短或突变形式等)。


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▍Synthelis Biotech产品列表


分类品名ProteinOriginFormatReferenceQuantity分子量
Viral ProteinsE1Envelop protein 1Hepatitis C virusProteoliposomePL01110µg, 20µg, 50µg, 100µg, 200µg, 500µg21 kDa
Viral ProteinsE2Envelop protein 1Hepatitis C virusProteoliposomePL01010µg, 20µg, 50µg, 100µg, 200µg, 500µg21 kDa
Viral ProteinsN-proteinNucleocapsid Protein (COVID-19)SARS-Cov 2 virusSolubleS-14410µg, 20µg, 50µg, 100µg, 200µg, 500µg47,7 kDa
Viral ProteinsF5LVaccinia virus major membrane proteinVaccinia virusProteoliposomePL00710µg, 20µg, 50µg, 100µg, 200µg, 500µg39.0 kDa
Viral ProteinsHCV p7Hepatitis C virus P7HCV virusProteoliposomePL04210µg, 20µg, 50µg, 100µg, 200µg, 500µg7 kDa
GPCRsAPJ/ARApelin ReceptorHumanProteoliposomePL06110 µg, 50 µg ,100 µg44.7 kDa
GPCRsB2RBradykinin receptor 2HumanProteoliposomePL08010 µg, 50 µg ,100 µg47.0 kDa
GPCRsBRBacteriorhodopsinBacteriaProteoliposomePL02710 µg, 50 µg ,100 µg29.4 kDa
GPCRsCCR1C-C chemokine receptor type 1HumanProteoliposomePL02110 µg, 50 µg ,100 µg43.7 kDa
GPCRsCCR2aC-C chemokine receptor type 2, isoform aHumanProteoliposomePL02210 µg, 50 µg, 100 µg44.5 kDa
GPCRsCCR2bC-C chemokine receptor type 2, isoform bHumanProteoliposomePL02310µg, 20µg,100 µg, 200 µg42 kDa
GPCRsCCR5C-C chemokine receptor type 5HumanProteoliposomePL02410µg, 20µg ,100 µg , 200 µg, 500 µg,bulk40 kDa
GPCRsCXCR4C-X-C chemokine receptor type 4HumanProteoliposomePL01610 µg, 50 µg, 100 µg43 kDa
GPCRsCXCR4-DetergentC-X-C chemokine receptor type 4HumanDetergentD01625µg ,100 µg ,500 µg,bulk40 kDa
GPCRsGLP1RGlucagon-like peptide 1 receptorHumanProteoliposomePL06710 µg, 50 µg, 100 µg55.5 kDa
GPCRsGPR50G-protein coupled receptor 50HumanProteoliposomePL09510 µg, 50 µg, 100 µg67.4 kDa
GPCRsGPR54G-protein coupled receptor 54HumanProteoliposomePL09710 µg, 50 µg ,100 µg45.2 kDa
GPCRsHMOPMu-type opioid receptorHumanProteoliposomePL025--
GPCRsMT1Melatonin receptorHumanProteoliposomePL02810µg, 20µg ,100 µg , 200 µg, 500 µg,bulk40 kDa
GPCRsRXFP1Relaxin receptor 1HumanProteoliposomePL06810 µg, 50 µg ,100 µg89.1 kDa
Ion Channelskir1.1bATP-sensitive inward rectifier potassium channel 1 isoform bMouseProteoliposomePL03110µg, 20µg,100 µg, 200 µg, 500 µg, bulk42.7 kDa
Ion Channelskv1.2Potassium voltage-gated channel subfamily A, member 2RatProteoliposomePL03710µg, 20µg ,100 µg , 200 µg, 500 µg,bulk57 kDa
Ion Channelskv1.3Potassium voltage-gated channel subfamily A, member 3MouseProteoliposomePL03610µg, 20µg ,100 µg , 200 µg, 500 µg,bulk58 kDa
Ion ChannelsVDAC1Voltage-Dependent Anion Channel 1HumanProteoliposomePL02910 µg, 50 µg ,100 µg30.7kDa
Ion ChannelsVDAC1 – DetergentVoltage-Dependent Anion Channel 1HumanDetergentD02910 µg, 50 µg, 100 µg30.7kDa
LigandsSDF1aStromal cell-derived factor 1HumanSolubleS06910 µg, 50 µg ,100 µg10.7 kDa
PorinsOEP24Outer envelope pore protein 24, chloroplasticPlantProteoliposomePL04010 µg, 50 µg ,100 µg24 kDa
PorinsOprFOuter membrane porin FBacteriaProteoliposomePL04510 µg, 50 µg, 100 µg40 kDa
Enzymesgp91phox (Nox2 subunit)gp91phoxHumanProteoliposomePL00810µg, 20µg ,100 µg , 200 µg, 500 µg,bulk55 kDa
EnzymesKMOKynurenine 3-monooxygenaseHumanProteoliposomePL00510µg, 20µg ,100 µg , 200 µg, 500 µg,bulk55,8 kDa
EnzymesNox2, p22 PhoxCytochrome b-245 light chainHumanProteoliposomePL03910 µg, 50 µg ,100 µg23,5 kDa
EnzymesNox4Nox4HumanProteoliposomePL05910µg, 20µg ,100 µg , 200 µg, 500 µg,bulk67 kDa
EnzymesPORCNProtein-Cysteine N-palmitoyltransferase porcupineHumanProteoliposomePL00610 µg, 50 µg, 100 µg55.5 kDa
EnzymesTFTissue factorHumanProteoliposomePL05310µg, 20µg ,50µg, 100 µg , 200µg, 500 µg,bulk33 kDa
EnzymesT7 RNA PolT7 RNA PolymeraseBacteriophage T7SolubleS19210 µg, 50 µg, 100µg100.1 kDa
EnzymesDsbCDisulfide bond isomeraseE.coliSolubleS197customized quantity on request.25.4 kDa
ReceptorsCLDN 18.2Claudin 18.2 ProteinHumanProteoliposomePL11910 µg, 50 µg, 100 µg30 kDa
Transcriptional regulatorsAROSActive regulator of SIRT1HumanProteoliposomeS05210µg, 20µg ,100 µg , 200 µg, 500 µg,bulk15,4 kDa
TransportersBakBcl-2 homologous antagonist killerHumanProteoliposomePL03825µg ,100 µg ,500 µg,bulk17 kDa
TransportersEspHCytoskeleton-modulating effector of enterohaemorrhagic and enteropathogenic Escherichia coliBacteriaProteoliposomePL05110 µg, 50 µg, 100 µg21.9 kDa
TransportersHCV p7Hepatitis C virus P7VirusProteoliposomePL04225µg ,100 µg ,500 µg,bulk7 kDa
TransportersNhaANa(+)/H(+) antiporter NhaAE. coliProteoliposomePL03210 µg, 50 µg, 100 µg43.9 kDa
TransportersUCP1Mitochondrial brown fat uncoupling protein 1MitochondriaProteoliposomePL04710 µg, 50 µg, 100 µg35.1 kDa
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艾美捷科技代理HMGBiotech品牌产品。


高迁移率族蛋白B1(HMGB1)是一种高度保守的核蛋白,广泛分布于哺乳动物细胞。随着其晚期促炎作用的发现,HMGB1成为近年来研究的热点之一。HMGBiotech是

一家专注于为HMGB领域的研究人员和公司提供试剂、服务的公司;值得注意的是,HMGBiotech公司,是目前位数不多的,生产HMGB1蛋白氧化还原变体的供应商。


HMGB1在基因组的组织和表达中具有多种功能:当细胞因损伤(病毒、机械或化学创伤、中毒)而死亡时,HMGB1 被释放并被附近细胞中的受体吸收。此外,处于严重

压力下的细胞甚至在死亡前会分泌HMGB1;存活的细胞会发出一系列反应 - 炎症 - 并试图替换死细胞并重建受损组织。HMGB1能够促进恢复和再生,;然而,过多的

 HMGB1与脓毒症、关节炎、动脉粥样硬化和癌症转移有关。HMGBiotech主要产品包括:


(1)细胞

来自 Hmgb1 野生型和 Hmgb1 敲除细胞的对照细胞裂解物

Hmgb1敲除小鼠胚胎成纤维细胞

Hmgb2敲除小鼠胚胎成纤维细胞


(2)质粒

HMGB1 质粒

RAGE 质粒


(3)蛋白质试剂盒

HMGB1亚型试剂盒


(4)不含LPS的HMGB1重组蛋白


(5)稳定标记的蛋白质

HMGB1 15N 标记用于质谱和 NMR

用于核磁共振的 SDF-1 15N 和 13C

SDF-1 15N 用于质谱和 NMR


(6)抗体

ANTI HMGB1单克隆抗体

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